Urtcevel (Ursodeoxycholic acid) 250 mg
23046USD

Urtcevel (Ursodeoxycholic acid) 250 mg

SKU:2019
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Urtcevel (Ursodeoxycholic acid) hepatoprotective agent, has a choleretic effect, reduces the synthesis of cholesterol in the liver, its absorption in the intestine and its concentration in bile, increases the solubility of cholesterol in the biliary system, stimulates the formation and secretion of bile
Active substance:Ursodeoxycholic acid
Pharmacological group:Hepatoprotectors
Formulation:Capsules
Dosage mg:250
In stock
$30
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Instructions for Urtcevel (Ursodeoxycholic acid) 250 mg

Description:

Solid gelatin capsules №0 are white in colour. The contents of the capsules are white or almost white powder.

Active substances Urtcevel
Ursodeoxycholic acid

Brief description
Hepatoprotector with cholelytic and cholelititic action.

Composition for one capsule Urtcevel:

Active substance:; ursodeoxycholic acid - 250.0 mg.
Auxiliary substances:;cornstarch, silica colloid (aerosyl), magnesium stearate.
Gelatinic capsule composition:;titanium dioxide, gelatine.

Pharmacological effect:

Hepatoprotector. Ursodeoxycholic acid is a bile acid. The invention substantially reduces the cholesterol content in bile by dispersing the cholesterol and forming a liquid crystal phase. It affects the enterohepatic circulation of bile salts, reducing reabsorption in the intestines of endogenous more hydrophobic and potentially toxic compounds. Ursodeoxycholic acid has a direct hepatoprotective effect and reduces hepatotoxicity of bile hydrophobic salts in in vitro studies. It affects immunological responses by reducing the pathological expression of Class I HLA antigens on hepatocytes and inhibiting the production of cytokines and interleukin. Ursodeoxycholic acid reduces the lithogenic bile index, increasing the bile acid content. Promotes partial or total dissolving of cholesterol gallstones during oral administration. It has a choleretic effect.

Testimony Ursodeoxycholic acid:

  • Cholesterol gallstones in the gallbladder and general bile duct in patients where surgical or endoscopic 
  • treatment is not possible. 
  • Cholesterol stones of the gallbladder and general bile duct with a diameter of not more than 1.5-2 cm after
  • extracorporeal lithotripsy or mechanical lithotripsy. 
  • Primary biliary cirrhosis (before advanced fibrosis and cirrhosis). 
  • Chronic active hepatitis with cholestatic syndrome. 
  • Acute hepatitis, 
  • liver cystic fibrosis, 
  • congenital bile duct atresia. 
  • Biliary reflux-esophagitis and gastritis. 
  • Biliary dyspeptic syndrome in cholecystopathy and biliary dyskinesia. 
  • Prevention and treatment of cholestatic syndrome caused by hormonal contraceptives. 
  • To normalize liver function in patients receiving cytostatic therapy, 
  • as well as in patients with alcoholic liver lesions. 
  • Liver and other organ transplantation (auxiliary treatment).

Method of use and doses Ursodeoxycholic acid:

Set individually. It is usually used at a dose of up to ten mg/kg/day. The daily dose is taken once in the evening. Duration of treatment depends on the indications.
Interaction with other drugs Urtcevel
The simultaneous use of cyclosporin with an unpredictable increase in absorption and an increase in the concentration of cyclosporin in the blood plasma. A case is described in which the concentration of ciprofloxacin in blood plasma is reduced in a patient receiving ursodeoxycholic acid.

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