Composition Vermox:
mebendazole 100 mg
Excipients:
sodium lauryl sulfate
colloidal silicon dioxide
magnesium stearate
sodium saccharinate
talc, corn starch
lactose monohydrate
Pharmacodynamics Vermox:
Mebendazole is an anthelmintic drug with a wide spectrum of action.
The active substance of the drug Mebendazole, mebendazole, selectively disrupts the formation of cell tubulin in helminths, which leads to inhibition of transport and absorption of nutrients, in particular, glucose utilization is inhibited.
As a result, autolysis of the intestinal canal of the helminth develops, leading to its death. After oral administration, the drug is slightly absorbed.
A small part of it, getting into the blood, is 90% bound to plasma proteins and metabolized in the liver
Indications Vermox:
- Enterobiosis
- ascariasis
- hookworm
- strongyloidosis
- trichocephalosis
- trichinosis
- teniosis
- echinococcosis
- alveococcosis
- capillariosis
- gnatostomosis
- mixed helminthiases.
Side effects Anti-parasite:
Dizziness, nausea, abdominal pain. When used in high doses for a long time: vomiting, diarrhea, headache, allergic reactions (skin rash, urticaria, angioedema), increased activity of hepatic transaminases, hypercreatininemia, leukopenia, anemia, eosinophilia, hair loss, hematuria, cylindruria.
Special conditions Anti-parasite:
when using Mebendazole(within 24 hours after taking the drug) alcohol is prohibited
Contraindications Vermox:
nonspecific ulcerative colitis;
Crohn's disease;
liver failure;
children's age (up to 2 years);
pregnancy and lactation;
Hypersensitivity to any component of the drug.
1. Plasma pharmacokinetics and muscle residue dynamics of mebendazole in Carassius auratus
2. Mebendazole in parasitic infections other than those caused by soil-transmitted helminths
3. Safety of Mebendazole Use During Lactation: A Case Series Report
4. Mebendazole
6. In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells
