Vestibo (Betahistine) pills

Instructions for Vestibo (Betahistine) pills

English Product Name
Vestibo

Release Form
Table 8 mg: 28 or 30 pcs.
table 16 mg: 28 or 30 pcs.

Description Vestibo:

White or almost white tablets, round, flat, with beveled edges, marked "B16" on one side and risked on the other.

1 table
betagistina dihydrochloride 16 mg

Auxiliaries:
C90 - 4 mg, cellulose microcrystalline - 66 mg,
lactose monohydrate - 140 mg,
silicon colloid dioxide - 5 mg,
crospovidone - 12 mg, stearine 9 mg.

10 pcs. - blisters (3) - cardboard packs.
14 pcs. - blisters (2) - cardboard packs.

ATX codes
N07CA01 Betahistine

Clinical and pharmacological groups / Group affiliation
Drug Betahistine to improve microcirculation of the labyrinth used in pathology of the vestibular apparatus

Active substance Vestibo
betagistina dihydrochloride

Pharmacotherapeutic group Vestibo
Hystamine drug Betahistine

Storage conditions
The drug Betahistine should be stored in a dry, light-protected place, out of reach of children at a temperature not exceeding 25°C.

Expiry Date
Shelf life - 3 years.

Indications Vestibo:

• a watermelon of the inner ear;
• vestibular and labyrinth disorders, including dizziness,
• noise and pain in the ears
• headache
• nausea
• vomit
• hearing loss
• vestibular neuritis
• maze
• benign positional vertigo (including after neurosurgery);
• Mener's disease
• Vertebrobasil insufficiency, post-traumatic encephalopathy, atherosclerosis of brain vessels (as part of comprehensive therapy).

Method of application, course and dosage Vestibo:

The drug in tablets of 8 mg should be administered 1 tab. 3 times/day.
The drug in tablets of 16 mg should be administered 1 tab. 3 times/day.
The drug in tablets of 24 mg should be administered 1/2-1 tab. 2 times/day.
Maximum daily dose - 48 mg. Treatment is long.
Pills should be taken indoors during meals, without chewing, drinking a small amount of liquid.

Pharmacological effect:

Synthetic analog of histamine. It is a weak agonist of histamine H1 receptors and a rather powerful antagonist of histamine H3 receptors. It has histamino-like and vasodilatizing effect. It affects cochlear blood flow and central vestibular apparatus.

The action of the drug includes vasodilation in the inner ear (indirectly through histamine H3- and H1-receptors), inhibiting effect in respect of vestibular nuclei (through histamine H3-receptors) and pulse activity of ampoule receptors. By direct agonistic action on histamine H1 receptors of inner ear vessels and precapillary sphincters of microcirculatory channel located in vascular stripe (stria vascularis), as well as intermediaries through histamine H3 receptors, improves microcirculation and permeability of internal ear capillaries, normalizes the pressure of endolymphs in the maze and snail, increases blood flow in the basillary artery.