Instructions for Amorolfine nail polish vial
English Product Name
5% d/nail drug varnish: fl. 2.5 ml or 5 ml
Nail polish is medicinal in the form of clear liquid from colorless to light yellow.
amolphine hydrochloride 55.7 mg,
which corresponds to the content of amorolphin 50 mg
Agents: triacetine - 10.5 mg, ammonium copolymer methacrylate (type A) - 125 mg, ethyl acetate - 150 mg, butyl acetate - 50 mg, ethanol 95% - up to 1 ml.
Pharmacotherapeutic group Amorolfine
The pharmacological effect of said preparation consists in the antifungal properties thereof for external use. It can both prevent the development of fungal infections and destroy existing microorganisms. The drug acts on fungal cell membranes, mainly by interfering with sterol synthesis. In this way, it reduces ergosterol while also accumulating abnormal non-planar sterol stereoisomers. It is effective against yeasts of the genus Candida spp., Pityrosporum spp., Malassezia spp., Cryptococcus spp., dermatophytes Trichophyton spp., Microsporum spp., Epidermophyton spp., molds such as Altemaria, Hendersonula, Scopulariopsis, fungi of the family Dematiaceae (Cladosporium, Fonsecaea, Wangiella), dimorphic fungi Coccidioides, Histoplasma spp., Sporothrix, as well as actinomycetes.
Treatment of fungal nail infections caused by dermatophytes, yeasts, and molds (in cases involving no more than two thirds of the nail plate) requires special attention and prophylactic measures.
A number of guidelines should be followed to help prevent fungal nail lesions.
Method of application
It is important to note that the use of the drug should be carried out externally. Dosage and duration of treatment depend on the individual indication and form of drug used in therapy.
Nosology (ICD codes)
Mycosis of nails
Candidiasis of the skin and nails