Exeter (Terbinafine) cream 15 gr

Instructions for Exeter

Composition Exeter (Terbinafine):

100 g of cream Exeter contains:

active substance: 
Terbinafine hydrochloride - 1.0 g. 
Excipients: benzyl alcohol - 1.0 g; polysorbate-60 - 5.0 g; sorbitan stearate - 2.4 g; cetyl alcohol - 6.0 g; isopropyl myristate - 6.0 g
cetyl palmitate - 3.0 g
sodium hydroxide - 0.122 g; water - 75.478 g.

Pharmachologic effect Terbinafine Cream:

An Exiter antifungal drug for external use with a wide range of antifungal activity. In small concentrations, terbinafine has a fungicidal effect against dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton violaceum, Trichophyton tonsurans, Microsporum canis, Epidermophyton floccusom). Moderately sensitive: mold (mainly Candida albicans) and dimorphic fungi (Pityrosporum orbiculare (also known as Malassezia furfur)). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic. Terbinafine specifically modifies the early stage of sterol biosynthesis in fungi by inhibiting the squalene epoxidase enzyme located on the cell membrane of the fungus. This leads to a deficiency of ergosterol and to intracellular accumulation of squalene, which causes the death of the fungal cell. Exiter does not affect the metabolism of hormones or other drugs

Indications for use Exeter (Terbinafine Cream):

An antifungal drug Exiter for external use with a wide range of antifungal activity. In small concentrations, Terbinafine has a fungicidal effect against dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton violaceum, Trichophyton tonsurans, Microsporum canis, Epidermophyton floccusom). Moderately sensitive: mold (mainly Candida albicans) and dimorphic fungi (Pityrosporum orbiculare (also known as Malassezia furfur)). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic. Terbinafine specifically modifies the early stage of sterol biosynthesis in fungi by inhibiting the squalene epoxidase enzyme located on the cell membrane of the fungus. This leads to a deficiency of ergosterol and to intracellular accumulation of squalene, which causes the death of the fungal cell. Exiter does not affect the metabolism of hormones or other drugs.

Indications Exeter Cream:

cream Exeter is used to treat fungal infections of the skin caused by pathogens sensitive to Terbinafine:

• trichophytosis;
• microsporia;
• epidermophytosis;
• rubrophytes;
• candidiasis of the skin; 
• multi-colored lichen.

Contraindications Exeter Cream:

Hypersensitivity to Terbinafine, to other components of the drug; children's age (up to 12 years), lactation.

Dosage and administration:
Outwardly. Adults and children over 12 years old. Before applying the cream Exeter, it is necessary to clean and dry the affected areas of the skin. The cream is applied once or twice a day to the affected areas of the skin and adjacent areas with a thin layer, slightly rubbing. In case of infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the place of application of the cream can be covered with gauze, especially at night.
The duration of treatment Exeter depends on the indication and severity of the disease. The average duration of treatment Exeter: Dermatomycosis of the trunk, legs: 1 time per day for 1 week.
Dermatomycosis of the feet: 1-2 times a day for 1-2 weeks. Candidiasis of the skin: 1-2 times a day for 1-2 weeks. Multi-colored lichen: 1-2 times a day for 2 weeks.

Release form Exeter (Terbinafine Cream):

Cream Exeter for external use 1% together with instructions for use is placed in a cardboard box.