Instructions for Ezlor solution tablets (Desloratadine)
ATC codes
R06AX27 Desloratadine
Clinical-pharmacological groups / Group affiliation
Histamine receptor blocker. Anti-allergy drug Desloratadine
Active substance
desloratadin
Pharmacotherapy group
H1-histamine receptor blocker
Storage Conditions
In a place protected from light at a temperature not higher than 25 ° C. Store in a place not accessible to children.
Best before date
Shelf life is 3 years.
Description
Oval double convex dispersible tablets, white or almost white, dosage 5 mg - with risk
Active substances
Desloratadin
Release form
Tablets
Composition
Ingredients for 1 tablet: Active substance: Desloratadine - 2.5 mg. Auxiliary substances: calcium hydrophosphate dihydrate - 85.0 mg, cellulose microcrystalline - 25.0 mg, sodium carboxymethyl starch - 3.0 mg, aspartame - 2.5 mg, magnesium stearate - 1.2 mg, silicon dioxide colloidal - 0.8 mg.
Active substance: Desloratadine - 5.0 mg. Auxiliary substances: calcium hydrophosphate dihydrate - 170.0 mg, cellulose microcrystalline - 50.0 mg, sodium carboxymethyl starch - 6.0 mg, aspartame - 5.0 mg, magnesium stearate - 2.4 mg, silicon dioxide colloidal - 1.6 mg.
Testimony:
Allergic rhinitis (elimination or relief of sneezing, nasal congestion, mucus release from the nose, itching in the nose, itching of the sky, itching and redness of the eyes, tear), urticaria (reduction or elimination of skin itching, rashes).
Contraindications:
Increased sensitivity to Desloratadine, other components of the drug Desloratadine or to loratadine, pregnancy and breastfeeding period, childhood age up to 1 year, phenylketonuria.
Method of administration, course and dosage:
The tablet should be swallowed whole, without chewing, washed down with a small amount of water. It is desirable to take the drugDesloratadine at the same time of day, regardless of the time of meals.
Adults and adolescents aged 12 years - 1 tab. (5 mg) 1 time / day.
Application for kidney disorders
Use with caution in case of severe kidney failure.
Terms of Sale
No prescription.
Use in children
It is contraindicated to children under 12 years of age.
Nosology (ICD codes)
J30.1
Allergic rhinitis caused by plant pollen
J30.3
Other allergic rhinitis (year-round allergic rhinitis)
L50
Urticaria
Pharmacological effect Desloratadine
Histamine H1 receptor blocker (long acting). It is the primary active metabolite of loratadine. It inhibits the cascade of allergic inflammation reactions, including the release of anti-inflammatory cytokines, including interleukin IL-4, interleukin IL-6, IL-8 and interleukin IL-13, and the release of proinflammatory chemokines (RANTES), and the production of superoxide anions by activated polymorphnonuclear neutrophils
