Instructions for Indomethacin 10 rectal suppositories
English Product Name
Indometacin Sopharma
Dosage form
suppositories rect. 50 mg, 100 mg
Description Indomethacin:
Rectal suppositories 1 suppository.
Indomethacin 50 mg
6 pcs. - PVC containers (1) - packs of cardboard.
ATX Codes
M01AB01 Indometacin
Clinical and pharmacological groups / Group affiliation
NSAIDs
Active ingredient
indomethacin
Pharmaco-therapeutic group
Anti-inflammatory agent for topical use
pharmachologic effect Indomethacin:
NSAIDs, a derivative of indoleacetic acid. It has an anti-inflammatory, analgesic and antipyretic effect. The mechanism of action is associated with the inhibition of the COX enzyme, which leads to inhibition of the synthesis of prostaglandins from arachidonic acid.
Inhibits platelet aggregation.
When injected orally and parenterally, it helps to weaken the pain syndrome, especially pain in the joints at rest and during movement, reduce morning stiffness and swelling of the joints, increase the volume of movements. The anti-inflammatory effect develops by the end of the first week of treatment.
Testimony Indomethacin:
Joint syndrome (including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout), spinal pains, neuralgia, myalgia, traumatic inflammation of soft tissues and joints, rheumatism, diffuse connective tissue diseases, dysmenorrhea. As an aid for infectious and inflammatory diseases of the ENT organs, adnexitis, prostate, cystitis.
Designed for symptomatic therapy, pain reduction and inflammation at the time of application, the disease progression is not affected.
Method of use, course and dosage Indomethacin:
Set individually to take into account the severity of the disease. For adults, the initial dose is 25 mg two to three times daily. If there is insufficient clinical effect, the dose is increased to 50 mg three times a day. The long-acting medicinal forms are used once or twice daily. The maximum daily dose combined with any dosage form of indometacin is 200 mg.
When the effect is achieved, the treatment is continued for four weeks at the same or reduced dose. For prolonged use, the daily dose should not exceed 75 mg. Taken after eating.
For the maintenance treatment, 50-100 mg is rectally administered once per night.
Use in liver disorders Indomethacin
It is contraindicated in cases of pronounced liver dysfunctions. It is used with caution in liver diseases.
Application in elderly patients
It is used with caution in elderly patients.
Use in children
It is contraindicated for children under 14 years of age.
- Nosology Indomethacin (ICD codes)
- H66
- Pus and unspecified mean otitis
- I00
- Rheumatic fever without mention of heart involvement
- I01
- Rheumatic fever with heart involvement
- I09
- Other rheumatic heart diseases
- J01
- Acute sinusitis
- J02
- Acute pharyngitis
- J03
- Acute tonsillitis
- J31.2
- Chronic pharyngitis
- J32
- Chronic sinusitis
- J35.0
- Chronic tonsillitis
- M05
- Seropositive rheumatoid arthritis
- M10
- Podagra
- M15
- Polyarthrosis
- M19.9
- Arthrosis unspecified
- M25.5
- Joint pain
- M32
- Systemic lupus erythematosus
- M33
- Dermatopolimiosite
- M34
- Systemic sclerosis
- M42
- Spinal osteochondrosis
- M45
- Ankylosing spondylitis
- M47
- Spondylosis
- M54.1
- Radikulopathy
- M54.3
- Ishias
- M54.4
- Lumbago with Sciatica
- M54.9
- Dorsalgia unspecified
- M70
- Soft tissue diseases related to load, overload and pressure
- M71
- Other bursopathy
- M79
- Other soft tissue diseases not classified elsewhere
- M79.0
- Rheumatism unspecified
- M79.1
- Mialgia
- M79.2
- Neuralgia and Neuritis Unspecified
- N30
- Cystitis
- N41
- Inflammatory prostate diseases
- N70
- Salpingitis and oophorite
- N94.4
- Primary dysmenorrhea
- N94.5
- Secondary dysmenorrhea
- R07.0
- Sore throat
- R52.0
- Acute pain
- R52.2
- Other persistent pain (chronic)
- T14.3
- Dislocation, stretching and overtension of the capsule-bonding apparatus of the unspecified body region joint
