Instructions for Indomethacin rectal suppositories
ATC Codes
M01AB01 Indometacin
Clinical and pharmacological groups / Group affiliation
NSAIDs
Active substance
indomethacin
Pharmacotherapeutic group Indomethacin
Anti-inflammatory agent for local application
Indomethacin Berlin-Chemie 50 mg Rectal Suppositories – Targeted Relief for Pain and Inflammation
Indomethacin Berlin-Chemie 50 mg rectal suppositories offer a focused and efficient way to manage discomfort caused by inflammatory conditions. Designed for individuals who need dependable relief but prefer (or require) an alternative to oral medications, this formulation delivers the active ingredient indomethacin directly into the bloodstream through rectal absorption. This route allows the product to begin working without stressing the stomach, making it a practical option for people with sensitive digestion or those who experience irritation when taking tablets.
Product Overview
Each pack contains 10 rectal suppositories, with each unit delivering 50 mg of indomethacin, a well-established nonsteroidal anti-inflammatory agent (NSAID). These suppositories are crafted to dissolve smoothly, offering comfortable insertion and rapid absorption.
Indomethacin has been widely used to reduce inflammation, relieve pain, and support mobility. The rectal form provides an alternative delivery method that avoids the digestive tract and can be especially helpful during flare-ups of severe pain, gastrointestinal sensitivity, or when swallowing tablets is difficult.
Indications Indomethacin
- Indomethacin works by reducing the body’s production of prostaglandins — natural chemicals that trigger inflammation, swelling, and pain. By limiting these compounds, the medication helps relieve discomfort associated with:
- Joint inflammation
- Muscle or tendon irritation
- Swelling after injury
- Painful flare-ups of chronic conditions
- Discomfort accompanied by stiffness or reduced mobility
- Because it bypasses the stomach and liver’s first-pass metabolism, the suppository form may offer smoother absorption and consistent effects.
Key Benefits Indomethacin
1. Fast and Direct Absorption
The rectal route allows the active ingredient to enter the bloodstream efficiently. This can be especially useful in situations involving nausea or digestive sensitivity.
2. Gentle on the Stomach
People sensitive to oral NSAIDs often appreciate this form, as it avoids direct contact with the stomach lining.
3. Convenient for Acute Pain Episodes
For many users, suppositories act quickly and provide steady relief during periods of intense discomfort, nighttime pain, or limited mobility.
Who It May Be Helpful For
This product may be a supportive option for adults experiencing:
Inflammation-related pain
Discomfort associated with musculoskeletal conditions
Acute episodes of swelling
Pain that interferes with daily activities
Situations where oral forms of NSAIDs are not suitable
Many users choose rectal suppositories during severe flare-ups or when they want steady, dependable relief.
How to Use Indomethacin Indomethacin
The suppository is designed to melt at body temperature. To use:
Wash your hands thoroughly.
If needed, lightly dampen the surface of the suppository to make insertion more comfortable.
Gently insert into the rectum while lying on your side.
Remain lying down for a few minutes to allow it to settle.
It is recommended to use the product at night or during a period of rest to maximize comfort and absorption.
What to Expect
Most individuals notice easing of discomfort within a short period after use. Effects can vary based on metabolism, the severity of inflammation, and individual response. Continued use as directed can help maintain relief and support mobility.
Ingredients
Active ingredient: Indomethacin 50 mg
Suppository base: Specially formulated for smooth insertion and controlled melting
Storage
Keep the product in a cool, dry location away from heat sources. Avoid exposure to sunlight. Store out of reach of children.
Nosology (ICD codes) Indomethacin
K08.8
Other specified changes in teeth and their supporting structures (including toothache)
M05
Seropositive rheumatoid arthritis
M07
Psoriatic and enteropathic arthropathies
M08
Juvenile [juvenile] arthritis
M10
Gout
M15
Polyarthrosis
M25.5
Joint pain
M45
Ankylosing spondylitis
M79
Other diseases of soft tissue, not elsewhere classified
M79.2
Neuralgia and neuritis, unspecified
N30
Cystitis
N41
Inflammatory diseases of the prostate
N70
Salpingitis and oophoritis
N94.4
Primary dysmenorrhoea
N94.5
Secondary dysmenorrhea
R51
Headache
R52.0
Acute pain
R52.2
Other persistent pain (chronic)
