Instructions for Orvirem (Rimantadine) syrup for children 0.2% 100 ml
Orvirem (Rimantadine) syrup for children 0.2% 100 ml
English product name
Orvirem
Release form
Syrup for children
Description Orvirem:
Syrup [for children] in the form of a thick liquid of pink or light red.
1 ml 5 ml (1 tsp)
rimantadine hydrochloride 2 mg 10 mg
Auxiliary substances: sugar, alginate sodium, E122 dye, purified water.
100 ml dark glass bottles (1) - cardboard packs.
ATC codes
J05AC02 Rimantadine
Clinical-pharmacological groups / Group affiliation
Antiviral drug
Active substance Orvirem
Rimantadine hydrochloride
Pharmacotherapy group
Antiviral agent
Pharmacological effect Rimantadine:
Antiviral agent derived from adamantane; is active against various strains of influenza A virus (especially type A2). The polymer structure ensures a long-term circulation of rimantadin in the body, which makes it possible to use it not only for therapeutic, but also for preventive purposes. Inhibits the early stage of specific reproduction (after the virus enters the cell and before the initial transcription of RNA).
As a weak base, rimantadin acts by increasing pH by the endosome - the membrane-containing vacuoles that surround the viral particles after they enter the cell. Preventing acidification in these vacuoles inhibits fusion of the viral envelope with the endosome membrane, thus preventing the transmission of viral genetic material to the cell cytoplasm. Rimantadin also inhibits the escape of viral particles from the cell, i.e., interrupts transcription of the viral genome.
Testimony Rimantadine:
Early treatment and prevention of influenza A in adults and children (depending on the drug form).
Method of use, course and dosage Rimantadine:
Inside. The dosing regime is set individually, depending on the indications, the age of the patient and the dosage form used.
Use in children
The use of appropriate age categories in children is possible strictly according to indications, in recommended doses and dosage forms. Guidelines for the use of specific forms of rimantadine in children of different ages should be strictly followed.
- Nosology Orvirem (ICD codes)
- J10
- Influenza caused by an identified seasonal influenza virus
- Z29.8
- Other specific preventive measures
