Instructions for Troxevasin (Troxerutin) capsules
Release form, composition and packaging:
Hard gelatin capsules, cylindrical, yellow; capsule contents - yellow to yellow-brown powder.
-1 cap. troxerutin 300 mg Auxiliary substances: lactose monohydrate, magnesium stearate.
Shell composition: quinoline yellow dye (E104), sunset yellow dye (E110), titanium dioxide (E171), gelatin.
Clinical and pharmacological group: A drug used for venous circulation disorders. Vasoprotective
Pharmacological action:
The instruction was approved by the Pharmacological Committee of the Ministry of Health of Russia 14.12.2000
Troxevasin is a mixture of hydroxyethyl derivatives of rutin, in which tri-hydroxyethylrutoside with P-vitamin activity prevails.
Troxevasin has a pronounced venotonic, capillarotonic, anti-exudative and hemostatic effect. The drug reduces the permeability and fragility of capillaries, has a decongestant and anti-inflammatory effect. It blocks the venodilating effect of histamine, bradykinin, acetylcholine. It acts anti-inflammatory on periolenous tissue, has a pronounced antiplatelet effect. The drug Troxevasin does not have an embryotoxic, teratogenic and mutagenic effect.
Pharmacokinetics:
The plasma concentration of hydroxyethylrutoside reaches its maximum value 2- 8 hours after administration. T1/2 - about 24 hours. The bulk of the drug Troxevasin is excreted from the body with bile, and only a small part - with urine.
Indications:
Limb pain and swelling due to venous insufficiency of varying severity:
pre and postvaricose syndrome;
-acute superficial thrombophlebitis and periflebitis;
-ulcerative skin lesion and dermatitis against the background of varicose veins;
-bole and traumatic swelling: dislocation, stretching, contusion.
Dosing mode:
Inside, while eating. The initial dose is 1 cap. 2 For paresthesias and nocturnal tonic seizures, capsules are taken before bedtime and in the morning.
For maintenance therapy - 1 cap. for 2-4 weeks or more.
The success of treatment with the drug depends on its regular use in sufficient doses for a long time.
Side action:
Rarely: allergic skin reactions - urticaria, eczema, dermatitis.
Contraindications:
expressed sensitivity to the drug Troxevasin.
Overdose:
Troxevasin refers to harmless substances. No overdose cases have been described.
Drug interaction
There is no evidence of interaction with other drugs Troxevasin.
Terms and conditions of storage
In a dry, cool, light-protected place, at a temperature of 15 to 25 ° C.
Shelf life is 5 years.
The preparation cannot be used after the expiration date indicated on the package
